A neurosurgeon hits a child one night and, in a panic, commits a hit-and-run. The next day, she finds the boy on her ward of all places, a Romanian street kid who is being forced to pick pockets by a gang. The boy, who recognizes the driver from the accident, blackmails the doctor out of fear of the police and his gang. She is forced to give him shelter, but the two soon become friends and form a tight-knit community.

In the year 2030, young journalist Lena Bach witnesses a crime. A desperate pensioner takes the CEO of the wellness company "Prolife" hostage and tries to force him to confess. Just as the manager starts to talk, there is an explosion. Darow has allegedly detonated a hand grenade. The hostage-taker and his victim are killed and the bodies are immediately removed by special units of the German army. Then Lena meets an informant who has promised her important details of Darow's life via videophone in an illegal Berlin backyard hospital. She now knows: The hand grenade Darow was carrying was a plastic dummy. What really happened in the office of the CEO of "Prolife"?

Julia takes care of her paraplegic mother. After the tragic accident, the father had abandoned the family.

Life, death, and yet we know nothing.

Frank and Katrin return to Frankfurt to stop the scientist responsible for unleashing the plague of genetically mutated vermin upon the city.

Berlin Alexanderplatz; within 24 hours, various stories rotate between the heights and depths of the square, between the television tower and the subway shafts, between larger and smaller fates, that slowly but surely become entangled.