1964, in the Escambray mountains: the area is infested with counter- revolutionary bands which are trying to spread terror among the population and re-establish contact with the US, CIA. The murder of a man led to a reprisal to wipe out the bandits.

At the height of the 1980s AIDS epidemic, Cuban boxing champion Horacio's punishment for failing a drug test is to watch over the brash, combative Daniel, a patient in a sanatorium where HIV patients are compulsorily confined. The two collide as Daniel yearns for freedom while Horacio dreams of returning to the ring.