Through interviews with leading psychologists and scientists, Neurons to Nirvana explores the history of four powerful psychedelic substances (LSD, Psilocybin, MDMA and Ayahuasca) and their previously established medicinal potential. Strictly focusing on the science and medicinal properties of these drugs, Neurons to Nirvana looks into why our society has created such a social and political bias against even allowing research to continue the exploration of any possible positive effects they can present in treating some of today's most challenging afflictions.

The documentary follows one woman's quest to overcome anxiety, depression, and opioid addiction through the use of psychedelic medicines.