Durgeshnandini is a sweeping historical drama set against the backdrop of 16th-century India. This epic tale follows the intertwined destinies of Jagat Singh, a Mughal general, and Tilottama, a Bengali princess. Their love story unfolds amidst the turbulent Pathan-Mughal conflicts, leading to a series of dramatic events, including betrayal, loss, and ultimate triumph.

Gowri, a woman in search of her lover Suresh, joins a group of struggling roadside singers. Friendship grows between them as they achieve success, but things change when Suresh returns.

Siddhartho Chowdhury, a brilliant young medical student, is forced to leave his studies after his father's sudden demise. He is forced to navigate the high unemployment rate and the communist socio-political climate of 1960s Calcutta in search of a job. He lives in a flat with his younger, employed sister, revolutionary brother and widowed mother. The strain of the situation ultimately causes him to hallucinate.