Claire is the kind of woman who knows she doesn't want kids, but when she meets a guy at a frat party she gets more than he bargained for.

Lifelong friends Dave and Mitch are envious of the other's life. Mitch thinks Dave has it all: a beautiful, loving family and a high-paying job at a prestigious law firm. But Dave thinks Mitch’s stress-free playboy life without obligation or consequence is the real dream come true. One fateful drunken night, they both admit that they wish they had the other’s life while peeing in a fountain when lightning strikes. The next morning, they wake up, hungover, in each other’s bodies! With time not on their side, Mitch and Dave comically struggle to avoid completely destroying each other’s lives before they can find a way to get their old ones back.

Two female friends with very different ideals decide to start a beauty company together. One is more practical, while the other wants to earn her fortune and live a lavish lifestyle.