After her divorce, Sanjana moves to a cottage in the forest with her daughters and brother. However, she is tormented by attacks from an invisible force.

Tony works as a hit-man for gangster, Vikas Patil, who owes his allegiance to wealthy Raj Mallya. Raj Mallya is involved in marketing spurious and out-dated drugs, and as a result is the subject of an investigation by the Food & Drugs Administration's inspector Dr. Hargobind Gosai. Raj asks Vikas to take care of Hargobind through Tony, which Tony does, and in this manner, Raj is absolved of all wrong-doing. Then Tony meets with attractive starlet named Sapna, and falls head over heels in love with her. When Sapna tells him that she is engaged to be married to Dr. Ajay Saxena, he is heart-broken. Then a scandal breaks out, and Hargobind is implicated in the deaths of three children that were killed by Raj's spurious drugs. All the evidence points against Hargobind, and not a single lawyer is willing to take his case; his wife kills herself, and the marriage of his daughter has been canceled.

Big Brother is a story set in modern India which revolves around a small middle-class family composed of Dev Sharma Sunny Deol, his wife Aarti Priyanka Chopra, his mother Farida Jalal, brother Imran Khan and sister Prachi. Although they lead a simple and peaceful lifestyle, an incident occurs that changes their lives forever. The family is left with no choice but to leave Delhi and move to Mumbai in disguise. They start life afresh and all seems well until the ghosts of the past surface again. Things reach a point when Dev Sharma is prodded by his mother to take a course of action which not only avenges their plight but also take on the cause of the aggrieved in the country as a whole. The movement so created gets the support of the woman at large and the infirm who proudly proclaim him to be their Big Brother.