In search of a miracle, an American woman embarks on a journey to the Peruvian Amazon and finds hope in a community, through rituals involving an ancient psychedelic plant known as ayahuasca. With her perception forever altered, she forges a bond with a young indigenous shaman undergoing a crisis of his own, and a motley crew of psychonauts seeking transcendence, companionship, and the meaning of life and death.

An anxious screenwriter’s darkly comedic descent into madness in Hollywood’s twisted industry sees him mimic his screenplay’s murders, becoming a chilling true crime star.