The story of Julia, a disabled woman in a wheelchair and voice synthesizer, who's trapped psychologically by a cruel, manipulative caregiver. After the arrival of a mysterious man, Julia begins to question the day-to-day dramas and frustrations she's tolerated for years. An achingly genuine and profoundly moving drama about a woman born with cerebral palsy.

The film follows the story of Jamie, a struggling butch lesbian actress who gets cast as a man in a film. The main plot is a romantic comedy between Jamie's male alter-ego, "Male Jamie," and Jill, a heterosexual woman on set. The film's subplots include Jamie's bisexual roommate Lola and her cat actor Howard, Lola's abrasive butch German girlfriend Andi, and Jamie's gay Asian friend David.