PMS COP is the story of Mary, a police officer, who after being caught on television beating a rapist, is forced into an evil Pharmaceutical Company's drug trial for a PMS inhibitor known as Corybantic. After a tragic event Mary suffers a horrific side effect, and with her new found superhuman strength, she begins to systematically take out her vengeance on everyone in her path! Will Mary fight against her inner urge to destroy or could she become the first of a new secret weapons program designed by an evil corporation?

Strange things are happening in Druid Hills, Kentucky, known mainly for its voluminous corn output. Victims of monsters in cornfields begin cropping up, and witnesses are saying there are large Great White sharks swimming in the corn stalks.