Arizona Manhunt was the second entry in Republic's "Rough Ridin' Kids" series. Michael Chapin returns as Red, the precocious grandson of Sheriff White (James Bell), while Eilene Janssen likewise reappears as Red's best friend Judy. Once again, the two kids get involved with grown-up western desperadoes, in this case the outlaw gang formerly controlled by Judy's foster father.

A desert guerilla, with flashing scimitar, opposes a tyrannical prince and marries the caliph's daughter.

When newlyweds visit Las Vegas, the wife's shady past comes to the surface.