Notorious crooks "Hairpin" Annie and Sea Bass steal a suitcase on the train and discover that it is filled with scenarios. Its owner, Egbert Winslow, agrees to write a screenplay about the underworld with Sea Bass's help. Sea Bass, seeing a chance to expose a pal who has double-crossed him, describes "High-Shine" Joe and some of his underworld activities. Joe sees the film in a South American theater and recognizes himself. He goes to the motion picture studio determined to kill Egbert Winslow, but bank president Peyton, who has been robbed by Joe, appears simultaneously with the police and saves Winslow.

Needy Ham Hamilton is mistaken for a dog show judge and he takes advantage of the situation for material gain.

When Buffalo Bill Cody learns that the Union Pacific railroad is making its way through Kansas, he and other heroes of the Wild West join forces to build a town along the route.