Piroberta wants to fulfill the American dream and live in the United States, to achieve this she plans to leave on her new motorcycle. Unfortunately the motorcycle is retained by the police and she doesn't have the money to get it back, so she turns to the witch Dioselina, who recommends certain types of jobs with which she makes a profit.

The naughty and funny witch Dioselina provides esoteric services to her neighbors helping them with rituals and ridiculous oddments, until her success falls apart when Dr. Sarmiento, a corrupt politician closes her business. This situation motivates her to want to unmask the intentions of the politician, uniting with her neighbors in a campaign to give her her due.

Piroberta comes to live in a house that her aunt inherited, but in that house lives an evil spirit, and along with her friends, and the sorceress Dioselina, they will have to get out of there alive.

With the arrival of a new and mysterious inmate, known as El Coco, fear grips the place: stormy nights, unexplained deaths, and an atmosphere charged with tension. Desperate authorities turn to a unique group of comical prisoners to uncover the truth. Can they save themselves from this sinister creature?

Sagrario finally convinced El Mono Sanchéz to marry her and everything is ready for the big celebration with her friends. Moments before the wedding Sagrario stains her dress with blood and El Mono sees her in her wedding dress, these two unfortunate events make Dioselina panic and with the help of Don Jediondo creates a mysterious conjuring to counteract the terrible tragedy. But the potion falls into the wrong hands and the situation gets out of control.