UFC on ESPN 17: Santos vs. Teixeira was a mixed martial arts event produced by the Ultimate Fighting Championship that took place on November 7, 2020 at the UFC Apex facility in Enterprise, Nevada, part of the Las Vegas Metropolitan Area, United States. A light heavyweight bout between former UFC Light Heavyweight Championship challengers Thiago Santos and Glover Teixeira headlined this event.

UFC Fight Night 192: Smith vs. Spann was a mixed martial arts event produced by the Ultimate Fighting Championship that took place on September 18, 2021, at the UFC Apex facility in Enterprise, Nevada, part of the Las Vegas Metropolitan Area, United States. A light heavyweight bout between former UFC Light Heavyweight Championship title challenger Anthony Smith and Ryan Spann served as the main event.

UFC on ESPN 10: Eye vs. Calvillo was a mixed martial arts event produced by the Ultimate Fighting Championship that took place on June 13, 2020 at the UFC Apex facility in Enterprise, Nevada, part of the Las Vegas Metropolitan Area, United States. The women's flyweight bout between former UFC Women's Flyweight Championship challenger Jessica Eye and Cynthia Calvillo served as the new event headliner.

UFC on ESPN 21: Brunson vs. Holland was a mixed martial arts event produced by the Ultimate Fighting Championship that took place on March 20, 2021 at the UFC Apex facility in Enterprise, Nevada, part of the Las Vegas Metropolitan Area, United States. A middleweight bout between Derek Brunson and Kevin Holland served as the event headliner.