The new installment of the Sharknado franchise takes place 5 years after Sharknado 3: Oh Hell No! There have been no Sharknados in the intervening years, but now they’re appearing again in unexpected ways.

Alison, a teen, is facing pregnancy. With nowhere to turn, she finds herself in a "clinic" about to end her baby's life. Suddenly a man appears. His mop tells her he's the janitor. Conversation begins and it quickly becomes clear that this man is no mere janitor, but Jesus manifest. And he's come to save the life of her baby.

It's the 13th month of the 13th year of the new millennium.

Six friends having a weekly board game night are interrupted by a booming movie trailer voice from the sky. Inexplicably, they find themselves trapped in a Horror Movie. Who amongst them will turn into a homicidal killer? Who will be the sole survivor? And who will be the first to die in the shower? Struggling to break free from the stereotypes that would see them dead, each of the friends try to stay alive in whatever hopelessly desperate ways they can.

Six friends having a weekly board game night are interrupted by a booming movie trailer voice from the sky. Inexplicably, they find themselves trapped in a Horror Movie. Who amongst them will turn into a homicidal killer? Who will be the sole survivor? And who will be the first to die in the shower? Struggling to break free from the stereotypes that would see them dead, each of the friends try to stay alive in whatever hopelessly desperate ways they can.