Spike waves to a young woman driving a red pickup truck through the desert of Needles, California every day; it is the highlight of his day. In this combined animated and live-action special, we meet an aerobics instructor, Jenny, who wants to be a big city jazz dancer. She and Spike drive around looking at the desert scenery and spending some time at a roller rink. However, when Spike is accidentally thrown out of the skating rink he runs off and is pursued by people on a nighttime coyote hunt.

Lenny Brown moves to California to find his fortune in tax shelter investments. When the federal government changes the tax laws, poor Lenny finds himself $700,000 in hock with nowhere to turn. His friend, Joel, introduces him to cocaine to give Lenny that needed "boost". What ensues next is a descent into drug addiction and insanity as Lenny tries to regain control of his life, all the while needing that extra "boost".