Clips from assorted television programs, B-movies, commercials, music performances, newsreels, bloopers, satirical short films and promotional and government films of the 1950s and 1960s are intercut together to tell a single story of various creatures and societal ills attacking American cities.

A simple Connecticut farm girl is recruited by a distant relative, an aristocratic patroon, to be governess to his young daughter in his Hudson Valley mansion.

Cleo Moore stars as Mary Adams, whose first step on the road to ruin is a $25,000 robbery. Mary hides the money, then confesses to the crime, secure in the belief that she can dig up the loot upon her release from prison.

When composer George Harvey Bone wakes with no memory of the previous night and a bloody knife in his pocket, he worries that he has committed a crime. On the advice of Dr. Middleton, Bone agrees to relax, going to a music performance by singer Netta Longdon. Riveted by Netta, Bone agrees to write songs for her rather than his own concerto. However, Bone soon grows jealous of Netta and worries about controlling himself during his spells.

A former boxer turned taxi driver earns the scorn of his nagging wife and gets mixed up with jewel thieves.

Lt. Col. Glenn Manning is inadvertently exposed to a plutonium bomb blast and although he sustains burns over 90% of his body, he survives. Then he begins to grow, but as he grows he starts losing his mind. By the time he stops he is 50 ft tall, insane and is on the rampage.

Virginia Cunningham is confused upon finding herself in a mental hospital, with no memory of her arrival at the institution. Tormented by delusions and unable to even recognize her husband, Robert, she is treated by Dr. Mark Kik, who is determined to get to the root of her mental illness. As her treatment progresses, flashbacks depict events in Virginia's life that may have contributed to her instability.

In 1865, a troop of Confederate soldiers led by Major Matt Stewart attack the wagon of gold escorted by Union cavalry and the soldiers are killed. The only wounded survivor tells that the war ended one month ago, and the group decides to take the gold and meet their liaison that knew that the war ended but did not inform the troop. The harsh Rolph Bainter kills the greedy man and the soldiers flee in his wagon driven by Major Stewart. When they meet a posse chasing them, Stewart gives wrong information to misguide the group; however, they have an accident with the wagon and lose the horses. They decide to stop a stagecoach and force the driver to transport them, but the posse returns and they are trapped in the station with the passenger. They realize that the men are not deputies and have no intention to bring them to justice but take the stolen gold.

When two outlaw gangs team up to rob gold shipments, the U.s. Army sends their ace-troubleshooter, Dan Parker, to the area. Sam Casey, the mystery-man behind the gangs, kills Parker's father, and this induces his sweetheart, Rita Starr, to side with the law-and-order faction. An attempt by Casey to kill Rita is foiled by Parker, which leads to a widespread gun-battle. Written by Les Adams

A policeman (Glenn Langan) with a pregnant wife (Adele Jergens) winds up chasing a payroll thief (Lon Chaney Jr.) into Mexico by helicopter.