Powder River Rustlers is a western film directed by Philip Ford in 1949. The railroad is coming and to get the townspeople's money. Shears Williams brings in a fake Agent who tells them they must raise $50,000 as their share of a railroad bridge. Railroad Agent Rocky Lane arrives and immediately spots the fake. A phony telegram assures Rocky his friend is still alive and he sets out to find him and his abductor.

A hack screenwriter writes a screenplay for a former silent film star who has faded into Hollywood obscurity.

A young doctor falls in love with a disturbed young woman and apparently becomes involved in the death of her husband. They head for Mexico trying to outrun the law.

Georgia Garrett is sent by jealous wife Elvira Kent on an ocean cruise to masquerade as herself while she secretly stays home to catch her husband cheating. Meanwhile equally suspicious husband Michael Kent has sent a private eye on the same cruise to catch his wife cheating. Love and confusion ensues along with plenty of musical numbers.

Police catch a break when suspected kidnappers are spotted on a train heading towards Union Station. Police, train station security and a witness try to piece together the crime and get back the blind daughter of a rich business man.

Career gambler Dan Milner agrees to a $50,000 deal to leave the USA for Mexico, only to find himself entangled with fellow guests at a luxurious resort and suspecting that the man who hired him may be the deported crime boss Nick Ferraro aiming to re-enter to the USA.