Escaping a Nazi prison train in war-torn Italy, an American and a British soldier set out for the Swiss border and find themselves leading a multi-national party of refugees for the Italian underground.

The titular Marie-Louise is a young French lass who is evacuated to Switzerland when her country is overrun by the Nazis. Suffering a nervous breakdown, she is given comfort and shelter by a wealthy family. Unfortunately, living in the lap of luxury makes Marie-Louise hesitant to return home to her mother and war torn home. Eventually the girl comes to her senses, but it isn't easy.