Marc Huestis edits interviews with 15 men, including himself, around a set of topics starting with "what is sex?" The men are gay, living in or near San Francisco. They talk about their first sexual experiences, the gay scene in San Francisco in the late 1970s, the pall cast by AIDS, the safe-sex movement, getting into serious relationships, the illness and death of partners, pornography, S/M and pain, race and stereotypes, personal fantasies, and bliss. Huestis has a thesis, that sex is going to be with us, so how best do we embrace it? His 15 subjects, archival footage, clips from porn films, and close-up looks at men loving men flesh out various answers.

A story of the LGBT struggle from the 1960s to the present, after the Stonewall riot sparked the militant action in New York that was to spread around the world. From San Francisco to Paris via Amsterdam, between the first Gay Pride, the election of Harvey Milk, the French "decriminalization", the AIDS epidemic and the first homosexual marriages, these few decades of struggle are embodied through numerous testimonies of actors and actresses of this revolution rainbow.