Taking place on the Navajo Nation, Cloyd Begay (Beau Benally), has been a victim of alcohol abuse and domestic violence throughout his childhood in result having him resorting to alcohol to repress his memories. As he is willing to take responsible for his life and as husband and father, his drinking buddies Jimmy (Gerald Vandever) and Marty (James Junes) cultivate in having Cloyd continue their carefree lifestyle of drinking and partying, preventing him to change. All the while, his wife Lorraine (Kim White) and son Michael (KJ White) begin to lose hope in him and seriously consider leaving him. As the ensuing events unfold, it leads him making the choice that will change his life forever.

This crime drama is about Candy Price's struggle with Jimmy Jr, the son of Jimmy Falcione, aka Big Jimmy, now retired in Phoenix, and losing his mind to Alzheimer's, so his son is controlling operations. After a successful robbery, Jimmy Jr disrespects Candy for the last time. She snaps violently at Jimmy Jr, and now he wants her dead. Still, she tries her luck by running to Phoenix to ask Jimmy's dad for forgiveness, but Big Jimmy only sees her as a problem. Candy wants out, and now, finally will do anything to have her way. The outfit has no idea just how much heat Candy has in her.

In a post- apocalypse future, a band of Native Americans sit on one of the largest remaining oil reserves in the world - and are forced into conflict with a powerful Chinese corporation.

Faced with the murder of three medicine men, Navajo police must find the culprit. That the murders appear to be the work of a Skinwalker, or bad medicine man, complicate and illuminate the detective's work.