After several American and British military personnel are killed in suicide attacks throughout southeast Asia, the U.S. begins to suspect a plot by the Vietnam government. To uncover the truth, the U.S. army calls upon a former commando who is looking for his long-lost son in Vietnam. While his military commanders want to see the commando succeed in his mission, his political overseers have a different set of plans.

Ryan Travers has just been released from a prison in Bangkok, Thailand, after serving a five-year sentence for murder. His parents, running an antique shop in the area while waiting for their son to be released, are killed in an explosion perpetrated by the local mob after refusing to pay protection money. Ryan's news go from bad to worse when he learns his sister Katie is seriously ill and will need an operation. With only a dead end job at a construction site after his release, Ryan learns about a local underground fight ring and decides to enter to raise the money for his sister's medical fees and search vengeance.

It started with the rape of his daughter, then the killing of her boyfriend. He takes the law into his own hands and has his revenge. Branded as a vicious killer by the underworld, the syndicate blackmails him into becoming their hitman. As he gets more and more tied up in the world of drugs, prostitution and death, he decides he wants out. No one gets out of the syndicate alive. It then becomes a battle for survival, him against them in a desperate act of street warfare. His life is his prize.

An assassination in the Philippines is caught on film by kickboxer Christy, which leads to her death at the hands of radicals intent on disrupting peace talks. Her sister Kat, a Los Angeles police officer, comes to Manila to try and bring justice to the people responsible. She enters the kickboxing tournament in order to get closer to the nefarious agents, and begins unravelling the twisted plan while narrowly evading the wrath of the Death Brigades.