Agatha Gone is the story of Agatha, a submissive yet kindhearted girl who lives with her abrasive and selfish half-sister Gwen. We are taken on a journey through the eyes and memories of Agatha, as she struggles with the love she has for Gwen, and the abuse she endures.

Rya, Cora, and Zuriel visit their long-lost friend Claudia, only to find her mysteriously ill. Their reunion is interrupted by a violent gang led by The Sores, causing tension and sadness. With Claudia's mother detached and Claudia feeling hopeless, the friends must confront their own fears to offer her hope.