Stand-up comedian Kate thinks her life has no meaning and is not worth continuing. When she’s diagnosed with breast cancer, even the universe seems to agree with her. However, a close encounter with death – and four other women on the chemo ward – might just change her mind and even her life.

Edward, a gay novelist saddled with caring for his elderly mother, finally finds himself on the brink of literary success. With pressure to go on a US book tour mounting, the last thing Edward needs is his friends jetting off to Spain for an impromptu Pride holiday, leaving their mothers on his doorstep! Over a chaotic weekend, he has to juggle his burgeoning career with the care of four eccentric, combative, and wildly different ladies.