Patagonia narrates the journeys of two women - one looking for her past, the other for her future. The film inter-cuts between their stories, in which one of them travels south to north through the Welsh springtime and the other east to west through the Argentine autumn.

Víctor Tellez is an intellectual, world-weary film critic who prefers to think in French and eschew the clichés of romantic movies...until he finds himself living a sappy, feel-good love story of his own.

Clara and Alejandro move into a new house. A few days later, he goes on a work trip and she is left alone, surrounded by moving boxes. That chaos makes her accept a series of random invitations that will take her away from the hermetic world she lives in.

Seemingly abandoned, a young woman walks through the porous city of Buenos Aires with her camera, finding potential mothers at every turn.

Tensions rise when a doctor (Daniel Veronese) pressures his teenage son to follow in his footsteps.

The life of Berta Muller, a successful writer, is shaken when, at the peak of her career, she is exposed in the media for plagiarism. Far from taking responsibility, he will deny the accusations and try to justify himself ridiculously, even if it means exposing all his darkness.