With Saitama no rappa 2 (AKA 8000 Miles 2 – Girls Rapper), Yu Irie tells the story of amateur girl rappers who dream of a small big-time. The film opens with Saitama 1 B-boys, Ikku and Tom coming to town. They run into young Ayoma (Maho Yamada), inspiring her to gather her girlfriends and work up their rap routine.

Reiko, a child guidance worker, tries to persuade Misaki, who is pregnant, to stop drinking. Since her first child was born intellectually disabled, Misaki is determined to stop and goes to see an obstetrician, and is prescribed an unapproved drug to curb her alcoholism.