College life getting you down? Switch to Seika College where the students are getting a whole new lesson in sexual education! Michiru's classes were dull and boring until her classmates, Chie, Saori and Takeru, started taking extra classes at a new night school. Utilizing subliminal messaging, the school helps their students ace their daytime college exams. Unfortunately, the school's professor forgot to mention the process has a few sexual side effects... The next day Saori's in for the sexual education of a lifetime! Classmates begin masturbating, her professor is fondling the other students before her eyes, and Saori is getting so hot she's literally exploding! Then, on the way home, Chie finds her sexual appetite soaring. She'll take any man, or thing, that can relieve her inner burning desires! Can innocent Michiru uncover the truth behind the evil night school and the mysterious deaths of her friends before anyone else dies? Or is she fated to become another victim?

This time around, the demon is trapped inside sexy but wholesome schoolgirl Izumi, but is unable to get up to its usual tricks (rampant orifice invasion) thanks to the crucifix that she wears around her neck. Out to locate and destroy the monster are a nun and a priest, but their efforts are hampered by Izumi's evil protector Sakiko, who does her best to help the girl realise her true tentacle-thrashing potential (and, in a Carrie-style side story, also settle the score with a group of nasty school bullies who have been making Izumi's life hell).