Fatty comes up with a plan to prank his cowboy buddies. He announces that his sister Kitty is coming to visit, but it's not at all what his friends expected.

Disgusted by the unsanitary conditions of the flat in which she lives, Patty Gordon, a pretty young artist, writes anonymously to John Richardson, asking him to investigate the conditions of his tenements. Plainly dressed, Richardson goes down to the tenements and rents an apartment for himself, so that he may see firsthand whether or not there is cause for complaint. He is accompanied by his dog, Dick, a valuable thoroughbred collie, who, seeing Patty's door open, enters and makes friends with her.

When Wall Street dynamo Richard Strong rescues Edwin Rossiter from financial ruin, Rossiter is so grateful that he persuades his daughter Elinor to marry their benefactor, although she does not love him. Instead, Elinor favors her distant cousin, Charles Dalton, a dissipated member of the aristocracy who weds Zoldene, an actress, on the day of Elinor and Strong's wedding. Soon after, Dalton wearies of Zoldene and renews his attention to Elinor, now estranged from her husband.

The train carrying all the cages filled with wild animals of the circus is wrecked, and bears, lions, leopards, elephants, kangaroos and monkeys escape down the track toward the village.

Glory Quayle, a natural-born mimic, leaves her country home, reaches London, goes on the stage, gains fame and affluence. John Storm, her country sweetheart, believing he has lost Glory forever, enters a monastery, tries to forget her, cannot kill his love, returns to the world, becomes a famous slum worker and friend of the poor.

Count Von Herbeck, the chancellor to the Grand Duke of Ehrenstein, is married but keeps the fact secret on account of his high ambitions. His wife, dying, writes him a letter urging him to make their little child a great lady. A lost film.

Beatrice Wilson, visiting her brother, a British officer in India, is sought in marriage by a native prince. She refuses him and he plots revenge. He incites the Sepoys to mutiny and they set fire to Jack Wilson's home and endeavor to abduct Beatrice. She is defended by her brother, who in the midst of the excitement is taken captive.

A psychological study of the effects of drug addiction on humanity. Helene Ford has been injected with heroin by an unscrupulous physician, causing her to act irrationally. Her husband Stephen, a noted artist, hires a model whom Helene, inflamed by their friend Jack Murray, suspects of having an affair with Stephen. The model is also addicted to drugs and convinces Stephen to try heroin to forget his troubles. Both Stephen and Helene then become addicted to drugs. They abandon their home and then separate, after which Stephen resorts to crime to support his heroin addiction. During an escape from the police after a robbery, Stephen encounters Helene again, this time near death. She sacrifices her own life to shield her husband, but Stephen and his former model plunge to their deaths.

In 64 A.D., Marcus Superbus is Prefect of Rome. When the Emperor Nero decides to renew persecution of the Christians, Marcus opposes him, fearing for the safety of Mercia, the Christian woman whom he loves. Through the machinations of the Empress Poppaea and other women at court, Tigellinus, Nero's agent in the war against the Christians, convinces Nero to have Mercia arrested. Marcus appeals to the emperor for mercy, but is told that she can be saved only by renouncing Christianity. Waiting to enter the arena to be killed, Mercia steadfastly refuses to reject her religion, despite Marcus' pleas. Finally, Marcus is converted by her and they enter the arena to face death together.

A strike among the hotel waiters is on. The papers are full of it. Chester Colton, and Harris Baldwin, young college chaps, read that waiters are needed in all the big hotels and restaurants. They apply for positions at Belfonte's restaurant. Harris secures a job as head-waiter and Chester is appointed as one of the regular staff. Harris's fiancée has an engagement with her chum to take dinner with her at the restaurant. They boys pay so much attention to the girls that they neglect the other patrons, who make a kick and complain to the proprietor.