In a small college town, a recent spate of grisly slayings dubbed the "sorority house murders" has led to rumors of a so-called "blood cult" at large, composed of a number of prominent local citizens. Despite the main perpetrator having apparently jumped to their death, the gruesome murders continue unabated, with each victim bearing the signature of the cult — a golden amulet depicting a dog's head left at the scene. Returning to his hometown following the murder of his brother, Michael begins to suspect that the blood cult may have had something to do with his sibling's grim demise. Finding the authorities ineffectual, Michael teams up with his elderly childhood neighbor Gracie Moore — whose husband has recently fallen prey to the cult — and together the pair hatch a plan to put an end to the gruesome goings-on.

Female students on a college campus are being killed and their body parts used for blood sacrifices.