Blondie organizes Housewives of America to perform home-front wartime duties, including guarding the local dam... Blondie for Victory was twelfth in Columbia's series of comedy films based on Chic Young's popular comic strip Blondie. Anxious to do her bit for the war effort, Blondie joins the Housewives of America, a home defense league. Husband Dagwood soon finds that Blondie is neglecting her responsibilities at home in favor of her war work; also disgruntled are Dagwood's chauvinistic boss Mr. Dithers and a newlywed husband whose wife is never home thanks to the defense league.

Mr. Dithers invites the Bumsteads on a South American cruise. Somehow Dagwood winds up as the female drummer in the ship's band, while Penny Singleton gets to show off her Broadway background in some lively musical numbers.

Dagwood Bumstead must receive a college diploma or lose his job with the Dithers Construction Company. Not wishing to be separated from her husband, Blondie enrolls in college as well. But Leighton College rules stipulate "No Married Couples", forcing Blondie and Dagwood to pretend that they're not married. This causes quite a dilemma when coed Laura Wadsworth begins flirting with Dagwood and Rusty Bryant does the same with Blondie. And Blondie's discovery of a very pleasant secret threatens to expose her and Dagwood's marital status too.

Cookie is born, producing unmitigated joy in the Bumstead household. Adding to the chaos a new baby always creates is the appearance of Hans Conried as a cynical author who becomes caught up in the Bumstead lifestyle.

Mr. Dithers is trying to encourage a businessman to build a war-time manufacturing plant on land he owns while Dagwood tries to prevent the businessman from learning his daughter is involved in a local theatre production.

Mr. Dithers is trying to encourage a businessman to build a war-time manufacturing plant on land he owns while Dagwood tries to prevent the businessman from learning his daughter is involved in a local theatre production.

Dagwood Bumstead, intending to buy a house, buys a horse instead. However, Dagwood quickly gets mixed up in a fox hunt, and Blondie must save the day.

Dagwood Bumstead, intending to buy a house, buys a horse instead. However, Dagwood quickly gets mixed up in a fox hunt, and Blondie must save the day.

Blondie and Dagwood are about to celebrate their fifth wedding anniversary but this happy occasion is marred when the bumbling Dagwood gets himself involved in a scheme that is promising financial ruin for the Bumstead family.

Baby Dumpling, the six-year-old son of Blondie and Dagwood Bumstead disappears from sight during his first day at school. While Dagwood frantically combs the city in search of the boy, Baby Dumpling spents a nice, safe afternoon with poor little rich girl Melinda Mason, who with her new playmate's help arises from her sickbed to walk across the room for the first time in months.