After WW2, a Los Angeles crime ring uses a complex scheme, involving a freight ship, a junkie, and a corrupt health officer, to smuggle drugs into the USA.

Jesse W. Haywood (Don Knotts) graduates from dental school in Philadelphia in 1870 and goes west to become a frontier dentist. Penelope "Bad Penny" Cushing (Barbara Rhoades) is offered a pardon if she will track down a ring of gun smugglers. She tricks Haywood into a sham marriage as a disguise. Haywood inadvertently becomes the legendary "Doc the Haywood" after he guns down "Arnold the Kid".

Army despatch rider Hondo Lane discovers a woman and her son living in the midst of warring Apaches, and he becomes their protector.

Roy Fleming is a small-town kiddie-ride operator who is deathly afraid of heights. After learning that his father has signed him up for the space program, Roy reluctantly heads for Houston, only to find out upon arriving that his job is as a janitor, not an astronaut. Anxious to live up to the expectations of his domineering father, Roy manages to keep up a facade of being an astronaut to his family and friends. When NASA decides to launch a layperson into space to prove the worthiness of a new automated spacecraft, Roy gets the chance to confront his fears.

There's a deficit of good, honest women in the West, and Roy Whitman wants to change that. His solution is to bring a caravan of over 100 mail-order brides from Chicago to California. It will be a long, difficult and dangerous journey for the women. So Whitman hires hardened, cynical Buck Wyatt to be their guide across the inhospitable frontier. But as disaster strikes on the trail, Buck just might discover that these women are stronger than he thinks.

A dairy owner's son takes a job as milkman with a rival company.

After arriving in Texas to escape a scandal back east, lawyer Sam Houston just wants to hang out his shingle, keep a low profile, and stay out of any political intrigue. However, when President Jackson personally orders him to lead the fight for Texan independence, he overcomes his reluctance to become involved and leads his compatriots to a string of victories over the Mexican army.

Fighting in the Civil War a man accidently kills his friend. Returning to Abilene after the war he finds his former sweetheart about to marry the brother of the man he killed. To pay his debt he not only refuses to win her back but takes the job of Sheriff, a job he doesn't want, when the brother asks him. Still haunted by the killing he refuses to carry a gun. But there is trouble between the ranchers and the farmers and when he finds the brother murdered he straps on a gun and heads after the killer.

The wall to Surprise Valley has broken, and Jane Withersteen is forced to choose between Lassiter's life and Fay Larkin's marriage to a Mormon.

As a Civil War veteran spends years searching for a young niece captured by Indians, his motivation becomes increasingly questionable.