After having had a ride with a hitchhiker, shot by some friends in a small town in Lazio, in one of them there is an old abbot monastery with a haunted man.

Army colonel Gabriele Moresco and twelve of his soldiers occupy a hospital in Sicily, Italy, taking every patient and doctor as hostages and giving an ultimatum to the government: if they won't admit their role in hiding proof of the use of depleted uranium in the Balkan Wars and the subsequent countless cases of cancer among Italian soldiers in 56 hours, all the hostages will be killed. Negotiator Paolo Manfredi is called to save the hostages, not knowing that his wife and daughter are among them.

A brave scientist has been studying thousands of cases related to alien abductions. By placing abductees under hypnosis, he arrives at the unsettling discovery that for thousands of years, a variety of extra-terrestrial races have been installing their active memories in abducted people's brains. These alien races exploit a powerful source of energy that only humans have: the Soul.

Francesco is an entrepreneur in the building industry. His company is near to collapse if it doesn't win a deal to build a new school complex. It needs at least 60 million liras to participate to the deal, but all the banks refuse to lend the money. A corrupt bank employee introduces him to Claudio, apparently an assistant of Sergio, Francesco's old school friend. Sergio is an accountant available to lend Francesco the money he needs. Francesco wins the deal, but soon he discovers that Claudio is not what he says.

Angelo Roncalli, born in Sotto Il Monte in 1881, is known for his profound spirituality as well as his extraordinary goodness from the young years of his life. When he feels a need to serve God, Angelo goes to study theology in Bergamo, and in Apollinare School (Rome) and becomes a priest. During his studies, he gets to know his two dearest friends, Mattia and Nicola. Very soon, most people see marvelous talents in him, including his wide knowledge and a constant readiness for sacrifice. The Holy See makes him go further to bishop and cardinal, and the Holy Father sends him to various places as a representative of the Church. When Pius XII dies on October, the 9th, 1958, 77 year-old Angelo goes to Rome, to conclave to choose a new pope. However, this time, it is him who hears gentle words of Jesus "Tu es Petrus!" ("You are Peter!") and from October, the 28th leads the church as pope John XXIII

Clashing with his father Paolo after coming home late, 17-year-old Marco accuses him of being old and stifling. They time travel to the 1960s, where Paolo will be able to prove his son he too used to be hip.