A runaway criminal breaks into an eerie chateau, taking its two frightened chambermaids hostage. As night falls, a group of mysterious aristocratic women arrive and the criminal begins to realize the women are hiding a sinister secret.

The French intelligence service want to use a double agent to eliminate a terrorist groupe. To do this, the captain Duroc will give to the traitor a car filled with explosives. But the whole thing is a double trap. One of the officer of the Service, Leroy, has plan a dreadful blow to discredit his new director. He had chosen Duroc because is not supposed to be an intelligent agent.

A man is shot down in a provincial airport. Despite his wounds he manages to drag himself to his plane bound for Italy, unaware that the killers are already waiting for him at his destination. During the flight he reminisces about the events that led him there. His name is Matou and he was a Formula 1 champion before being banned from racing circuits for causing a fatal accident. Matou ran away in the company of Lena, his employer's girlfriend. But while they were in the open country they got shot at by mysterious pursuers, which was the beginning of a wild manhunt.

The lives of three Parisians - a color-blind painter, a radio show host and a perverted photographer - intertwine and go hilariously out of control.

With the help of her accomplice and little brother Sirieix, she makes a report on palliative home care, to enlighten patients and companions about this comfort and openness for the last trip, the final destination.