After their car breaks down in an eerie small town, a young couple are forced to spend the night in a remote cabin. Panic ensues as they are terrorized by three masked strangers who strike with no mercy and seemingly no motives.

After learning that one of their victims, Maya, is still alive, The Strangers return to finish the job. With nowhere to run and no one to trust, Maya soon finds herself in a brutal fight for survival against psychopaths more than willing to kill anyone who stands in their way.