Leónidas, an eccentric artist, enters an existential crisis, and seeing that his new art exhibit's success does not motivate him, he decides to fabricate a relationship between his wife and a younger couple, hoping this will generate some inspiration for his work and life. His plan fails, as his wife leaves him for the young man and becomes close friends with the young woman.

Santa, an eight-year-old girl from the desolate Bolivian Altiplano, embarks on a rollercoaster journey to take her mother from a life of misery into paradise. The two of them made a pact: when her mother passes, the girl would follow the stars and carry her body across the desert toward heaven, a place they are certain is physically real. Crossing the wilderness, Santa encounters a group of female wrestlers that help her on her way. Also, a gruff policeman who arrests Santa but soon suspects she has magical powers. He decides that to achieve his own salvation he must join Santa on her quest beyond the horizon.