On one random day in the San Fernando Valley, a dying father, a young wife, a male caretaker, a famous lost son, a police officer in love, a boy genius, an ex-boy genius, a game show host and an estranged daughter will each become part of a dazzling multiplicity of plots, but one story.

A transgender woman takes an unexpected journey when she learns that she had a son, now a teenage runaway hustling on the streets of New York.

Helen Harris has a glamorous, big-city life working for one of New York's hottest modeling agencies. But suddenly her free-spirited life gets turned upside down when she must chose between the life she's always loved, and the new loves of her life!

Rebellious, uncontrollable teenager, Rachel is hauled off by her dysfunctional mother to spend the summer with her estranged grandmother, Georgia. Her journey will lead all three women to revelations of buried family secrets and an understanding that - regardless what happens - the ties that bind can never be broken.

When their only daughter Blair leaves the family nest, Luther and Nora Krank decide to book an island cruise to beat the yuletide blues and just skip the holidays. But their decision to boycott tradition has the whole neighborhood in an uproar, and when Blair calls on Christmas Eve to announce a surprise visit with her new fiancée, the Kranks have just twelve hours to perform a miracle and pull themselves and their neighbors together to throw the best celebration ever!

An inventor of a secret process suddenly finds himself alone as both his friends and the corporation he works for turn against him.

When an explosion at a top-secret government lab injures an elderly janitor, no one could have expected the terrifying results. Exposure to mysterious chemicals causes him to undergo a bizarre transformation. He is slowly... incredibly... growing younger every day. Now, a ruthless CIA assassin will stop at nothing to take him prisoner and turn him into a government guinea pig. With his future on the line, the janitor goes on the run with his wife and a feisty female agent. All the while, he continues to transform... into a being with powers that are as deadly as they are unimaginable.

In the midst of a spat, film critic Terry Thorpe accidentally kills his lover. Though Thorpe covers his tracks, he raises the suspicions of a private investigator, who then tries to blackmail him. Thorpe also falls under the watchful eye of Detective Fred Stapelli, a cop who is intent on becoming a screenwriter. Before long, Thorpe's girlfriend, Kit, and Stapelli's wife, Patricia, are roped into the case.

Wealthy Sunny von Bülow lies brain-dead, husband Claus guilty of attempted murder; but he says he's innocent and hires Alan Dershowitz for his appeal.

A corporate lawyer's interest in a decade-old murder case is piqued by a new confession that could clear the convicted killer, who sits on death row.