The story is a funny love story between Anna Bremer, the Bundeskanzlerin of Germany and Guy Dupont, the President of France.

Out of the blue, actress Anna loses her job at a small municipal theater. Having just been on stage, she now finds herself in the dreariness of the local job center. At the insistence of her theater-enthusiastic caseworker, she takes over the management of an acting course for eight long-term unemployed people who are difficult to place. Despite enormous resistance to the compulsory training program, the frustrated lone fighters increasingly form a close-knit group with whom Anna stages Antigone. Surprisingly, the participants' private dramas become more and more turbulent and Anna also experiences a new beginning that she hadn't expected.

Christian Lukas, 22, is on the run. He took part in a drug study and together with his girlfriend Anna discovered the death of a fellow participant. However instead of investigating, the doctors covered up the incident. When Anna also starts showing signs of the deadly side effects Christian breaks out of the test center to get help. But neither police nor doctors believe his story since Christian suffers from paranoid schizophrenia. Only his sister Alice stands by him despite her also having serious doubts - until suddenly unknown pursuers show up. But what is the real story behind Christian's escape? Does the girl in danger really exist at all? Where is the line between psychosis and reality? Nocebo - a perception thriller.