Fresh off a night of partying, a trio of friends set their sights on their futures apart. But, a band of violent intruders arrive, seeking to unleash a plan of their own.

After losing his wife, the deranged and reclusive Dr. Henry Jekyll descends into a nightmare of grief and obsession - until he takes Sharcopine, an untested drug that warps his body into a bloodthirsty man-shark. Now driven by madness and love beyond the grave, Jekyll prowls the streets, hunting anyone who threatens his twisted relationship with his long-dead bride.