A girl born with enormous thumbs in the repressive era of the 1950s learns to turn her quirks into assets.

It is based on the true story of Michael Francke, who was the Head of Corrections for the state of Oregon before being murdered. Just before his murder, Francke visits his brother and informs him of a drug ring involving his prison colleagues. When Michael is killed, his brother begins his own investigation into the murder, leading him to more lies and deceit.

Portland, Oregon, 1971. Bob Hughes is the charismatic leader of a peculiar quartet, formed by his wife, Dianne, and another couple, Rick and Nadine, who skillfully steal from drugstores and hospital medicine cabinets in order to appease their insatiable need for drugs. But neither fun nor luck last forever.

In this loose adaptation of Shakespeare's "Henry IV," Mike Waters is a hustler afflicted with narcolepsy. Scott Favor is the rebellious son of a mayor. Together, the two travel from Portland, Oregon to Idaho and finally to the coast of Italy in a quest to find Mike's estranged mother. Along the way they turn tricks for money and drugs, eventually attracting the attention of a wealthy benefactor and sexual deviant.