Sophie is a twenty-year-old American who has lived her life in isolation, cut off from the world. While on vacation in Palermo with her sister, she meets Giulio and his group of Sicilian friends during her final 24 hours before returning to California. Eager to break free from her sheltered past, Sophie embarks on a whirlwind romance with Giulio.

Angela is a dedicated and sensitive carer. She is a widow. Her husband, as many other workers in the area, died from asbestos-related diseases. When the man responsible for the many deaths, now crippled, is hospitalised, she accepts his son’s offer to become his caregiver, hoping to take her revenge.