On a gloomy Sunday in Mexico City, three friends in their twenties look for a female friend that disappears at an after-party. As they believe the worse could be happening, and while confronting characters and situations that represent a fraction of the problems of contemporary Mexico, their dreams, concerns and fears come to light.

Seventeen-year-old Carlos doesn't fit in anywhere, not in his family nor with the friends he has chosen in school. But everything changes when he is invited to a mythical nightclub where he discovers the underground LGBTQ nightlife scene: punk, sexual liberty and drugs.

The De La Mora siblings concoct a mischievous plan to break into their old family home to retrieve a hidden treasure of significant importance.

1951, Mexico City. After synthesizing the main component of the contraceptive pill, young scientist Luis Miramontes deals with the religious and personal consequences of his groundbreaking invention.