The lives of Ted and Marion Cole are thrown into disarray when their two adolescent sons die in a car wreck. Marion withdraws from Ted and Ruth, the couple's daughter. Ted, a well-known writer, hires as his assistant a student named Eddie, who looks oddly similar to one of the Coles' dead sons. The couple separate, and Marion begins an affair with Eddie, while Ted has a dalliance with his neighbor Evelyn.

Born under unusual circumstances, Benjamin Button springs into being as an elderly man in a New Orleans nursing home and ages in reverse. Twelve years after his birth, he meets Daisy, a child who flits in and out of his life as she grows up to be a dancer. Though he has all sorts of unusual adventures over the course of his life, it is his relationship with Daisy, and the hope that they will come together at the right time, that drives Benjamin forward.

Called in to recover evidence in the aftermath of a horrific explosion on a New Orleans ferry, Federal agent Doug Carlin gets pulled away from the scene and taken to a top-secret government lab that uses a time-shifting surveillance device to help prevent crime.

Two fathers' lives intersect when one of them is involved in a terrible and sudden hit-and-run car accident that leaves the other's son dead. In response, the two men react in unexpected ways as a reckoning looms in the near future.

A troubled actor, a television show runner, and an acclaimed videogame designer find their lives intertwining in mysterious and unsettling ways.

In late 1970s Ohio, a group of friends filming a homemade zombie movie witness a devastating train derailment. Soon after, their quiet town is gripped by unexplained disappearances, strange phenomena, and a growing sense of fear, as they uncover that something terrifying has been set loose.

Set in the futuristic Metro City, Astro Boy (Atom) is a young robot with incredible powers created by a brilliant scientist in the image of the son he had lost. Unable to fulfill his creator's expectations, Astro embarks on a journey in search of acceptance, experiencing betrayal and a netherworld of robot gladiators, before returning to save Metro City and reconcile with the father who rejected him.

After withdrawing to the Chateau Marmont, a passionless Hollywood actor reexamines his life when his eleven-year-old daughter surprises him with a visit.

A girl, abandoned by her mother when she was three, moves to a small town in Florida with her father. There, she adopts an orphaned dog she names Winn-Dixie. The bond between the girl and her special companion brings together the people in a small Florida town and heals her own troubled relationship with her father.

In 1920s Vienna, a young girl receives a magical doll on Christmas Eve.