The Secret Call is adapted from The Woman, a play by William C. DeMille (brother of Cecil B.) Peggy Shannon plays Wanda Kelly, the daughter of a disgraced politician. Reduced to working as a switchboard operator, Wanda is privy to the many secrets and indiscretions of the clients of a big-city hotel. She also finds romance in the form of handsome Tom Blake (Richard Arlen). The huge cast of characters comes in handy for the film's multitude of subplots, none of which ever get their wires crossed. Peggy Shannon acquits herself nicely in her first major role, but by the end of the decade her career was in decline.

Just as Charlie is running for mayor on a purity platform, an old flame threatens to show his torrid love letters to his wife if he does not withdraw from the campaign.

Nora Clegg, an actress, marries Carl Brent, an unemployed young engineer, whose estimation of his worth and ability keeps him from getting a job. He finally acquires a position that will require him to go to Russia for a period of time, while Nora goes back to the stage during his absence. But he loses out on the job at the last minute, and rather than tell Nora he has failed again, he steals a roll of money from his prospective employer to buy some things for Nora and go out and have a good time before, she things, his departure. His departure is to jail rather than Russia and he hides the truth from Nora by having an acquaintance mail his letters from Russia. He then finds out that Nora is pregnant.