A group of international criminals steal a large emerald from a heavily guarded Colombian mine and they plan to sell it on the black market. Unfortunately, the evil Dr. Igor is also manipulating other criminals, as well as the ones who stole the emerald, for his own benefit. Santo, a Mexican wrestler/Interpol agent works with the Colombian authorities in an attempt to recover the emerald and to stop Dr. Igor and his subordinates, as well.

Three friends out to disprove cannibalism meet two men on the run who tortured and enslaved a cannibal tribe to find emeralds, and now the tribe is out for revenge.