The Mommy Returns tells the story of a mother, Ruby, who dies right on the day of her 25th wedding anniversary with husband, William. With her untimely death, she leaves behind her three children Amethyst, Topaz, and Sapphire. Ruby is also temporarily trapped in PURGA (short for Purgatory) with its guardian, and the pesky Manny, the chicken pet of San Pedro. When Catherine, a younger and prettier woman comes into the life of William, Ruby escapes from PURGA and returns to earth as a ghost to drive Catherine out of the family she left behind.

This is the story of Visayans coming to the MetroManila area in search of greener pastures. Dodong Valderama, a jack-of-trades orphan, and Santo Nino devotee, sis among them, trying his luck in a different place. He meets Inday and her Lola Angeling, also Visayan immigrants, who are fish vendors. Angeling dreams for her daughter to become a popular singer , and hopefully one day, this will get them out of the slums. Angeling is pursued by town widower Max. Dodong, whose idol is the late Flash Elorde, eventually finds a full time job as janitor in a boxing gym. Inday fails to win the town singing contest, much to the disappointment of Lola Angeling.With the help of friend Lao, Dodong pursues Inday until they become sweethearts, then husband and wife.

In the human world, Pen (SPENCER REYES) and Dong are best friends who are fond of playing computer games. on the other hand, at the computer world where the different computer characters live, there is one character in the name of M. Tyson (REZ CORTEZ) who was mad and envy to human.

Manuel, an overseas worker, cheats on his wife with the wife of his boss. His life begins to unravel as his infidelity is revealed.