70-year-old Malena gets a second chance at life when she magically turns into her 22-year-old self. Now, posing as "Maria" to hide her true identity, she becomes the lead singer of her grandson's band and tries to recover her dream of singing, which she had to give up at some point.

Miguel is a prominent writer of soaps that gets rid of a policeman who stops him for driving intoxicated by telling him the end of the current remake of the hit soap opera "Destiny of Love". This time, as Michael tells the police officer, Gabriela won't die and will get married. When the officer tells everyone that he knows the end of the melodrama nobody believes him, so he will watch Miguel in order to ensure he fulfills his promise. The actress who plays Gabriela has problems with the production department, so they ask the writers to kill Gabriela in the following chapters. Miguel will be in a series of entanglements while he decides whether it is better to ignore or evade his bosses or the harassment of this crazy fanatic police officer.

Some incidents occur on the dancing floor, and the ladies' restroom at a tropical club will change the life of a macho politician, a naive and subdued married woman, an unfaithful lesbian couple, a transsexual dreaming of a sex reassignment surgery and a smart school teacher who loses her head after a few drinks.

Recently widowed, Benito faces the jealousy of his daughters when, reunited by an old ford car, he finds a new love and new meaning for his life.

Film based loosely on the life of Mexican drug kingpin Ricardo Lopez.

When a father-son duo learns that they may not be biologically related, the two embark on a wild adventure through Mexico to find the truth.