Luisa is called to the bed of her dying mother Edith at Karlstein Castle. Before she dies, she tells Luisa that the Karlsteins are a family of vampires and that her ancestor, the original Count Karlstein, lies buried in the crypt. Afterwards, Luisa goes and finds the count's coffin and discovers that he is undead. As she takes Karine, her cousin as her lover, a police inspector, Ptuschko investigates a series of killings around the town, dismissing the locals who insist these are being caused by vampires.

After the death of Victor Frankenstein, two figures vie for control of his monster and the radical technology that created him: the scientist's daughter, and an immortal wizard assisted by a blind bird-woman with an unquenchable thirst for blood.

Dracula kills another innocent victim and Dr. Seward decides it's time to wipe him off the face of the earth. Armed with a hammer and a wooden stake, he arrives at Castle Dracula and duly dispatches the vampire Count. Next day, however, Dr. Frankenstein arrives with his assistant, Morpho, and a large crate containing the monster. Using the blood of a pub singer who has been abducted by his creation, the doctor brings Dracula back to life and uses him for his own ends. The Count and a female vampire continue to terrorise the town, so Dr Seward once again sets out for Castle Dracula. Unfortunately, he is attacked by the Frankenstein monster and left for dead. Amira, a gypsy, rescues him and summons up a werewolf to do battle with the forces of evil...