Stanley Ford leads an idyllic bachelor life. He is a nationally syndicated cartoonist whose Bash Brannigan series provides him with a luxury townhouse and a full-time valet, Charles. When he wakes up the morning after the night before - he had attended a friend's stag party - he finds that he is married to the very beautiful woman who popped out of the cake - and who doesn't speak a word of English. Despite his initial protestations, he comes to like married life and even changes his cartoon character from a super spy to a somewhat harried husband.

A struggling painter begins taking inspiration from the dreams of his friend and roommate, a comic book fan who narrates an adventure story while he sleeps, but unbeknownst to the latter, the artist of his favorite comic book lives in the same building as they do with the model for her drawings.

Jack Jackson, the greatest football player in Ridgefield College history, is disappointed that his only son Junior is an uncoordinated, allergy-ridden bookworm. He uses his athletic reputation and standing as #1 alumni contributor to pressure the coach to take Junior onto the team. In addition, he pays the tuition of Junior's financially needy classmate Bill Baker, a potential all-American, with the understanding that he will room with Junior and mentor him athletically and socially. Junior's initial efforts as quarterback prove disastrous and further complications arise when the room mates both fall in love with the same co-ed.

Bill Miller is an unsuccessful Broadway performer until his handlers convince him to enhance his act with a stooge—Ted Rogers, a guy positioned in the audience to be the butt of Bill's jokes. After Ted begins to steal the show, Bill's girlfriend and his pals advise him to make Ted an equal partner.

Wally Hogan has things going his way. He is the manager-trainer of Bullet Bradley, a fighter who has just won the lightweight championship. However, life suddenly takes a not-so-happy turn when Bullet gets drafted.

Depressed by the direction his life is taking, Harry decides to take his own life by jumping off the Manhattan Bridge. At the last minute he's stopped by old friend Milt Manville, a successful stock broker. Milt, however, is facing his own problem: he has fallen out of love with his argumentative wife, Ellen. In a misguided effort to solve both of their problems, he introduces Ellen to Harry, hoping the two will fall in love.

When Zachary and Elsa separate, each seems tempted to start a new love affair.