Kate Diamond owns the Roaring Falls Trading Post from where she directs her gang's gun-smuggling to the Indians. After she short-changes smuggler Stacey, his men attempt to steal the hidden guns, and attack her foreman Nebraska, but he is saved by Jimmy and "Cannonball" on their way to file a homestead claim at Canyon City. Jimmy renews a long acquaintance with Sheriff Harris and his daughter Jessica. The sheriff is wounded by half-breed Danny when he finds a rifle hidden in the latter's wagon, but Jimmy captures the outlaw, a go-between for Kate and the Indians.Wounded and in bed, Sheriff Harris ask Jimmy not to tell Jessica that she is only adopted and that Nebraska is really her father, although he believes her to be dead.

Jimmy and his pal Cannonball are hired by a rancher and horse breeder to capture Midnight, a wild stallion that has been interfering with local herds and has a reputation as a killer.

The Navajo Kid goes in search of the villains who murdered his foster-father and stole both ring and watch. The trail leads straight to Canyon City, Texas, and smooth cardsharp Honest John Grogan, who is in possession of both the stolen items. But Grogan has an ironclad alibi for the time of the murder, an alibi confirmed by none other than Sheriff Roy Landon.

Despite his unprepossessing screen personality, singing cowboy Jimmy Wakely was starred in a series of Monogram westerns, one of which was West of the Alamo. Wakely and comedy sidekick Lee "Lasses" White play a pair of government agents who work undercover to solve a series of baffling crimes. It comes to no one's surprise that the criminal mastermind is the town's leading citizen, in this case banker Clay Bradford (Jack Ingram). As was typical in the Wakely westerns, West of the Alamo is approximately 25 percent action and 75 percent musical. Among the guest warblers this time out is the Arthur Smith Trio, headed by a gospel singer who'd later emcee a popular religious TV talk show.

Cowhand Drake discovers gold on the ranch of his boss, Joe Stuart and makes a deal with crooked lawyer Mel Porter to induce Stuart to sell. The latter refuses, and also orders Bill Cameron not to see his daughter Laurie again. Foreman Johnny Mack, after intervening, quits after he sees Stuart hit Laurie while quarreling over her proposed marriage to Cameron. Peddler Alibi Terhune witnesses the killing of Stuart by Clem Kettering, hired by Porter, and is taken prisoner. Cameron is blamed for Stuart's killing, escapes jail, but is persuaded by Johnny to go back and stand trial. Johnny rescues Alibi and the two work together on clearing Cameron's name, and bringing the real culprits to justice.

Singing cowboy Whip Wilson, the foreman on a cattle drive, quits his job to pursue five bank robbers who murdered his brother.

Jimmy Wakely and his sidekick "Lasses" White run into trouble as they attempt to hire some cattle cars on the Cattleman's Railroad to take their herd to market. Rancher Joseph Colton has bought up all the cattle cars and intends to purchase the penniless line from principal stockholder Gywnn Randall. She is eager to sell to Colton but doesn't realize that he intends to force all the ranchers out of business once he has control of the line.

Jimmy and partner Dusty have bought a ghost town in the Cherokee strip. When they arrive they find their other partner Lasses has sold 51% to four crooks.