On March 10, 2020, hours before the United States came to a complete halt due to the pandemic, "The Brothers" gathered at Madison Square Garden to celebrate the 50th anniversary of the Allman Brothers Band, the last show the band played under that name, it was on October 28, 2014 at the Beacon Theater in Manhattan. The concert turned out to be the last public appearance for the musicians on stage for the whole year, this only added mystique to the event that closed the book on half a century of musical tradition. Featuring performances by original ABB drummer Jaimoe, along with Duane Trucks, Derek Trucks, Warren Haynes, Otil Burbridge and Mark Quinones, as well as guest appearances by original pre-ABB Second Coming keyboardist Reese Wynans and Chuck Leavell, who played with the band from 1972 to 1976.

The Brothers - Celebrating 50 Years of the music of The Allman Brothers Band performed at Madison Square Garden in New York City for one night only March 10, 2020. The Brothers- Jaimoe, Warren Haynes, Derek Trucks, Oteil Burbridge, Marc Quinones-were joined by Duane Trucks and Reese Wynans and special guest Chuck Leavell.

The film documents the Hard Working Americans' (Todd Snider, Dave Schools, Neal Casal, Duane Trucks, Chad Staehly, Jesse Aycock) beginnings... behind the scenes in the studio as the band collaborates on their self-titled debut album and on the road following the band close-up throughout their national tour