A group of sorority girls go up to a cabin in the woods accompanied by some boys. To their dismay, there is an escaped convict on the loose as well as the uncle of one of the girls. It's too bad that Uncle Ray is possessed by an Indian spirit turning him into a monster with a need for human blood.

Carnivorous aliens arrive unannounced at a Kansas family farm; two intergalactic bounty hunters soon follow, determined to blow them off the planet.

When his best friend dies of a heart attack, Ray Macklin becomes a man obsessed with his own mortality. Convinced that all his aches and pains are an indication of his imminent death, Ray's life turns into a slapstick farce of health-crazed anxiety and hypochondria.